Publications

  • Antonia Barry*, Sabrina F. Samuel*, Ines Hosni, Amr Moursi, Lauric Feugere, Christopher J. Sennett, Srihari Deepak, Shailendra Achawal, Chittoor Rajaraman, Alexander Iles, Katharina C. Wollenberg Valero, Ian S. Scott, Vicky Green, Lucy F. Stead, John Greenman, Mark A. Wade and Pedro Beltran-Alvarez  Investigating the effects of arginine methylation inhibitors on microdissected brain tumour biopsies maintained in a miniaturised perfusion system. Lab on a Chip (2023) https://doi.org/10.1039/D3LC00204G
  • Muresan P*, McCrorie P*, Smith F, Vasey C, Taresco V, Scurr D, Kern S, Smith S, Gershkovich P, Rahman R, Marlow M. Development of nanoparticle loaded microneedles for drug delivery to a brain tumour resection site. European Journal of Pharmaceutics and Biopharmaceutics 182: 53-61 (2023). 
  • McCrorie P, Rowlinson J, Scurr D, Marlow M, Rahman R. Detection of label-free drugs within brain tissue using Orbitrap secondary ion mass spectrometry as a complement to neuro-oncological drug delivery. Pharmaceutics 14: 571 (2022).
  • Jain A, Jobson I, Griffin M, Rahman R, Smith S, Rawson F. Electric field responsive nanotransducers for glioblastoma. Bioelectronic Medicine 8:17 (2022). 
  • Branter J, Cebrero ME, Diksin M, Griffin M, Castellanos-Uribe M, May S, Rahman R, Grundy RG, Basu S, Smith S. Genome wide expression and anti-proliferative effects of electric field therapy on paediatric and adult brain tumours. International Journal of Molecular Sciences 23(4): 1982 (2022). 
  • McCrorie P, Rowlinson J, Scurr D, Marlow M, Rahman R. Detection of label-free drugs within brain tissue using Orbitrap secondary ion mass spectrometry as a complement to neuro-oncological drug delivery. Pharmaceutics 14: 571 (2022).
  • Rhiannon Barrow, Joseph N Wilkinson, Yichen He, Martin Callaghan, Anke Brüning-Richardson, Mark Dunning, Lucy F Stead. SpheroidAnalyseR – an online platform for analysing data from 3D spheroids or organoids grown in 96-well plates.
    Journal of Biological Methods  (2022) doi: 10.14440/jbm.2022.388
  • Sourav Bhaduri , Clémentine Lesbats, Jack Sharkey, Claire Louise Kelly, Soham Mukherjee, Arthur Taylor, Edward J. Delikatny, Sungheon G. Kim and Harish Poptani. Assessing Tumour Haemodynamic Heterogeneity and Response to Choline Kinase Inhibition Using Clustered Dynamic Contrast Enhanced MRI Parameters in Rodent Models of Glioblastoma. Cancers (2022). https://doi.org/10.3390/cancers14051223
  • Koessinger AL, Koessinger D, Stevenson K, Cloix C, Mitchell L, Nixon C, Gomez-Roman N, Chalmers AJ, Norman JC, Tait SWG. Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts. Sci Rep. (2020) Sep 21;10(1):15361.
  • Gomez-Roman N, Chong MY, Chahal SK, Caragher SP, Jackson MR, Stevenson KH, Dongre SA, Chalmers AJ. Radiation responses of 2D and 3D glioblastoma cells: a novel, 3D-specific radioprotective role of VEGF/Akt signaling through functional activation of NHEJ. Mol Cancer Ther. (2020) Feb;19(2):575-589.
  • Clémentine Lesbats, Nitish Katoch, Atul Singh Minhas, Arthur Taylor, Hyung Joong Kim, Eung Je Woo, Harish Poptani. High-frequency electrical properties tomography at 9.4T as a novel contrast mechanism for brain tumors. Magnetic Resonance in Medicine (2020) https://doi.org/10.1002/mrm.28685

  • Clémentine Lesbats, Claire Louise Kelly, Gabriela Czanner, Harish Poptani. Diffusion kurtosis imaging for characterizing tumor heterogeneity in an intracranial rat glioblastoma model. NMR in Biomedicine (2020). https://doi.org/10.1002/nbm.4386

  • Smith SJ, Rowlinson J, Estevez-Cebrero M, Onion D, Ritchie A, Wood K, Diksin M, Lourdusamy A, Grundy RG, Rahman R. Metabolism based isolation of invasive glioblastoma cells with specific gene signatures and tumorigenic potential. Neuro-Oncology Advances 2(1): 1-12 (2020).
  • Smith SJ, Tyler BM, Gould T, Veal GJ, Gorelick N, Rowlinson J, Serra R, Ritchie A, Berry P, Otto A, Choi J, Skuli N, Estevez-Cebrero M, Shakesheff KM, Brem H, Grundy RG, Rahman R. Overall survival in orthotopic malignant glioma is significantly prolonged by neurosurgical delivery of combined etoposide and temozolomide from a thermo-responsive biodegradable paste. Clinical Cancer Research 25(16): 5094-5106 (2019).
  • Birch JL, Strathdee K, Gilmour L, Vallatos A, McDonald L, Kouzeli A, Vasan R, Qaisi AH, Croft DR, Crighton D, Gill K, Gray CH, Konczal J, Mezna M, McArthur D, Schüttelkopf AW, McConnell P, Sime M, Holmes WM, Bower J, McKinnon HJ, Drysdale M, Olson MF, Chalmers AJ. A novel small molecule inhibitor of MRCK prevents radiation-driven invasion in glioblastoma. Cancer Res. (2018) Nov 15;78(22):6509-6522.
  • Gomez-Roman N, Stevenson K, Gilmour L, Hamilton G, Chalmers AJ. A novel 3D human glioblastoma cell culture system for modelling drug and radiation responses. Neuro Oncol. (2017) Feb 1;19(2):229-241.
  • Ahmed SU, Carruthers R, Gilmour L, Yildirim S, Watts C, Chalmers AJ. Selective inhibition of parallel DNA damage response pathways optimizes radiosensitization of glioblastoma stem-like cells. Cancer Res. (2015);75(20):4416-28.
  • Smith SJ, Ward JH, Tan C, Grundy RG, Rahman R. Endothelial-like malignant glioma cells in dynamic three dimensional culture identifies a role for VEGF and FGFR in a tumor-derived angiogenic response. Oncotarget 6(26): 22191-22205 (2015).
  • Smith SJ, Wilson M, Ward JH, Rahman CV, Peet AC, Macarthur DC, Rose FRAJ, Grundy RG, Rahman R. Recapitulation of tumor heterogeneity and molecular signatures in a 3D brain cancer model with decreased sensitivity to histone deacetylase inhibition. PLoS One 7(12): e52335 (2012).